During Tokugawa Ieyasu's epic battle of Sekigahara, two samurai face off outside of history. In the heat of the duel between Kyoshiro and Demon Eyes Kyo, a shooting star slams into the plains, shattering the ground and engulfing both of them. Years later, Kyoshiro, now a medicine man, wanders the land with a forgotten past. Hidden deep inside him is the soul of his old opponent, Kyo, slayer of a thousand men. When the bounty hunter Yuya and Kyoshiro are thrown into battle, the medicine man's friendly personality retreats, and the world learns why Kyo is called a demon!